Canadian Medicines
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How effective is Amoxil against infectious diseases?

Amoxil - pharmacological preparation from the amino group. This is a broad-spectrum antibiotic, which action is based on active ingredient amoxicillin trihydrate. Use Amoxil only in case it is prescribed by your healthcare specialist. Be careful getting acquainted with the instructions before taking the drug.

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Some words about Amoxil and its principle of work

Amoxil is an aminopenicillin with the synthetic nature. It has limited antibacterial properties. Restrictions are as insensitivity to the microorganisms that produce penicillinase themselves and to certain types of other bacteria.

Since the present composition of Amoxil includes clavulanic acid, this preparation is resistant to penicillinase. This is a reason of the reduction in its cross-immunity to the drugs antimicrobial effects.

Amoxil is produced in tablet form in the following availavle doses:

  • 625 mg
  • 500 mg
  • 250 mg

You can find the powder form for dilution for infusion of 1.2g.

Amoxil tablets are packed in the blister, ten pieces each, and two blisters in a carton box.

When is necessary to take Amoxil?

Indications to use this medication are the following cases:

Amoxil may be prescribed in case of the diseases listed below:

  • For the treatment of infectious diseases of the gastrointestinal tract, hepatobiliary system of the body;
  • For the treatment of infectious diseases of the kidneys and urinary system of the body;
  • For the treatment of infectious diseases of bone and joints;
  • For the treatment of infectious diseases of the skin and soft tissues.

Amoxil is effective for infectious complications that arise in the postoperative period.

For the treatment of peptic ulcer diseases of the digestive tract and chronic gastritis Amoxil is used in a combination with metronidazole or clarithromycin.

What are the ways of using Amoxil?

Amoxil is taken in the form of infusion or orally.

Infusions are intravenous administration of the drug, which can be carried out as the droplets and the jet. The gap between the holding Amoxil infusion should be no less than eight - twelve hours.

The solution of the drug is administered immediately after preparation by diluting the powder. It is forbidden to store the solution in the finished form.

Amoxil average therapeutic dose for an adult is 1000/200 mg every eight hours. The maximum permissible dose is 100/200 mg with a six-hour interval.

In cases of surgical disposable dosage of Amoxil (1000/200 mg) is administered prior to anesthesia for the first time, and all following times- every six hours after surgery.

Doses of Amoxil for children

If Amoxil is necessary for the treatment of children, the following doses should be used:

  • children up to three months (up to four kilogram of body weight) once the drug is administered at a dose of 25/5 mg per kilogram of body weight of the baby, every twelve hours;
  • after the age of three months (more than four kilogram) administered 25/5 mg per kilogram of body weight every eight hours for a child.

Amoxil tablets are taken regardless of meals. They should be swallowed whole with pure water. The interval between doses of the tablets must not be less than eight hours.

Amoxil pills can be prescribed for kids in the following way:

  • 1-2 year old: 30 mg per day per kilogram of body weight of the child;
  • 2-5 year old: 125 mg within one reception;
  • 5-10 years old: 250 mg at one time;
  • Older than10 years old (with a body weight of more than forty kilograms): 250-500 mg at one time.

The maximum daily dose of the drug for children is 60 mg. Adult patients are allowed to take one gram.

Possible side effects of Amoxil

Amoxil can cause negative side effects in some patients as well as any other drug. If you notice at least one of the side effects listed below, it is necessary to inform your doctor. Check out which adverse reactions are possible during Amoxil treatment:

  • Allergic reactions such as: urticaria, angioedema, erythema, rhinitis, conjunctivitis, rarely - in the form of eosinophilia, painful joints, fever and anaphylactic shock;
  • From the side of the gastrointestinal tract: diarrhea, nausea, vomiting, developing of the superinfection.

If Amoxil is used in conjunction with metronidazole the following side effects are possible: anorexia, constipation, vomiting, nausea, pseudomembranous colitis, diarrhea, glossitis, stomatitis, pain in the epigastric, rarely - hepatitis, interstitial nephritis.

Prolonged use of Amoxil can cause seizures, depression, dizziness, loss of consciousness, ataxia, periodic neuropathy.

What consequences are possible in case of Amoxil overdose?

In case of overdose of this drug there are disorders of the gastrointestinal tract and observed violations of water-electrolyte balance. Rarely there is renal failure associated with impaired renal parenchyma after crystallization of amoxicillin. In this case, hemodialysis for elimination of Amoxil from the bloodstream should take place. Also for the treatment of overdose one should have activated charcoal, saline laxatives, gastric lavage.

Contraindications to use Amoxil

Amoxil is not recommended to be taken by those patients who have had the following diagnoses: an increased level of individual sensitivity to the main active ingredient of the drug and the auxiliary components, including cephalosporins and penicillins.

It is forbidden to use this medicine in case of having one of the mentioned diagnoses:

  • infectious mononucleosis
  • pregnancy and lactation
  • lymphocytic leukemia
  • serious violations in the hematopoietic system
  • diseases of the central and peripheral nervous system

Furthermore, Amoxil should not be used simultaneously with metronidazole.

Which analogs does Amoxil have?

Among the analogues of Amoxil there are the following: Panklav, Augmentin, Amoxicillin, Amoksikomb, Ospamoks, Vampiloks, Amofast, Amoxiclav, Baktoklav. One of them can be taken in case you have experienced side effects using Amoxil. In any case, don’t take the decision to change the drug without informing your doctor.